Hurricane Matthew has left 100 people dead in Haiti, the interior minister said on Thursday.
One local official, speaking to AFP, said 50 people had died in the southern town of Roche-a-Bateau alone.
New images from remote and cut off areas in the south-west of the country show scenes of devastation.
The hurricane has again been upgraded to a Category Four storm, the second highest hurricane classification, as it heads for the U.S state of Florida, the BBC reports.
Hurricane Matthew is already the deadliest Atlantic storm since 2012, when Hurricane Sandy directly killed at least 147 people.
Sandy was a category three storm.
Matthew is a category four, after being downgraded from category five – the highest classification.